Plugin vulnerabilities are not a new thing. The only novel thing about this one is the number of affected sites. It’d be like Askimet having a major remote control exploit. You can mitigate these issues by making sure your plugins are up-to-date. WordPress is not particularly hard to manage. There are lots of plugins and services that make it brainless (shoutout: Jetpack). So, this should be a non-issue.
While we’re talking about plugin vulnerabilities, you should go visit Marko Saric’s guide on securing your WordPress install. Lots of good advice in there. I personally like using Jetpack (with Askimet and Vaultpress), but there are lots of free tools that you can use to secure yourself.